Systemin (Synonyms: 系统素)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Systemin  (Synonyms: 系统素) 纯度: 98.75%

Systemin 是一种18个氨基酸的多肽，从番茄叶子中分离出来，可诱导产生超过15种防御基因。

Systemin (Synonyms: 系统素)

Systemin Chemical Structure

CAS No. : 137181-56-7

规格 价格 是否有货 数量
1 mg ￥990 In-stock
5 mg ￥2900 In-stock
10 mg ￥5200 In-stock
50 mg   询价  
100 mg   询价  

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Systemin 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Peptide Library

•同靶点产品:

•同靶点蛋白产品:

生物活性

Systemin, an 18-amino acid polypeptide, has been isolated from tomato leaves that is a powerful inducer of over 15 defensive genes.

体外研究
(In Vitro)

Systemin is readily transported from wound sites and is considered to be the primary systemic signal.The signal transduction pathway that mediates Systemin signaling involves linolenic acid release from membranes and subsequent conversion to jasmonic acid, a potent activator of defense gene transcription. The pathway exhibits analogies to arachidonic acid/prostaglandin signaling in animals that leads to inflammatory and acute phase responses[1]. Systemin, an 18-amino-acid peptide signal. Systemin is cleaved from the C-terminal region of a 200-amino acid precursor protein called proSystemin. Following the cloning of proSystemin gene, which represents a single locus in the tomato genome, several lines of genetic evidence indicate that Systemin acts as an upstream component of wound-induced signaling cascades leading to defense gene expression[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Systemin 相关抗体:
分子量

2010.30

Formula

C85H144N26O28S
CAS 号

137181-56-7
性状

固体

颜色

White to off-white

Sequence

Ala-Val-Gln-Ser-Lys-Pro-Pro-Ser-Lys-Arg-Asp-Pro-Pro-Lys-Met-Gln-Thr-Asp
Sequence Shortening

AVQSKPPSKRDPPKMQTD
中文名称

系统素
结构分类
  • Others
初始来源
  • 植物
  • 茄科
  • 番茄
  • 植物
  • 其他科
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料

纯度: 98.75%

Data Sheet (518 KB) SDS (252 KB)

COA (258 KB) RP-HPLC (110 KB) MS (186 KB) 元素分析报告 (205 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Ryan CA, et al. Systemin: a polypeptide signal for plant defensive genes. Annu Rev Cell Dev Biol. 1998;14:1-17.  [Content Brief]

    [2]. Sun JQ, et al. Systemin/Jasmonate-mediated systemic defense signaling in tomato. Mol Plant. 2011 Jul;4(4):607-15.  [Content Brief]

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