上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
D-Isofloridoside
D-Isofloridoside 是多糖前体之一,具有清除自由基、抑制 ROS 表达、抑制 MMP-2 和 MMP-9 的活性。
D-Isofloridoside Chemical Structure
CAS No. : 23202-76-8
规格 | 是否有货 | ||
---|---|---|---|
50 mg | 询价 | ||
100 mg | 询价 | ||
250 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
D-Isofloridoside, one of the polysaccharide precursors, has the activity of scavenging free radicals, inhibiting ROS expression, and inhibiting MMP-2 and MMP-9[1][2]. |
---|---|
体外研究 (In Vitro) |
D-Isofloridoside can reduce the activity of MMP-2/9, and can inhibit the expression of hypoxia-inducible factor-1α (HIF-1α) by regulating the downstream PI3K/AKT and MAPK pathways, thereby down-regulating the production of vascular endothelial growth factor (VEGF) in CoCl2-induced HT1080 cell. D-Isofloridoside can inhibit the activation of VEGF receptor (VEGFR-2), regulate downstream PI3K/AKT, MAPK, NF-κB signal pathways, activate apoptosis, and thus down-regulate the production of platelet-derived growth factor (PDGF) in VEGF-induced HUVEC[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
254.23 |
Formula |
C9H18O8 |
CAS 号 |
23202-76-8 |
结构分类 |
|
初始来源 |
|
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
纯度 & 产品资料 |
Data Sheet (524 KB) 产品使用指南 (1538 KB)
|
参考文献 |
|
所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务