Neogambogic acid

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Neogambogic acid 

Neogambogic acid 是藤黄的有效成分，可诱导细胞凋亡并具有抗癌作用。Neogambogic acid 对耐甲氧西林的金黄色葡萄球菌 (MRSA) 具有明显的抑制活性。

Neogambogic acid

Neogambogic acid Chemical Structure

CAS No. : 93772-31-7

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Neogambogic acid 相关产品

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生物活性

Neogambogic acid, an active ingredient in garcinia, induces apoptosis and has anticancer effect. Neogambogic acid has significant inhibitory activity toward methicillin-resistant Staphylococcus aureus (MRSA)[1][2].

体外研究
(In Vitro)

Neogambogic acid inhibits HCT-8, Bel-7402, BGC-823, A549, and A2780 cell proliferation, with an IC50 between 1.75 and 3 μM. Neogambogic acid induces A549 cells apoptosis arrested the cells to G0/G1 phase in vitro[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Neogambogic acid 相关抗体:
体内研究
(In Vivo)

Neogambogic acid arrests A549-induced tumor growth in nude mice[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

646.77

Formula

C38H46O9
CAS 号

93772-31-7
结构分类
  • Phenols
  • Monophenols
  • Ketones, Aldehydes, Acids
初始来源
  • 植物
  • 其他科
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (529 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Wang K, et al. The mechanism of neogambogic acid-induced apoptosis in human MCF-7 cells.Acta Biochim Biophys Sin (Shanghai). 2011 Sep;43(9):698-702.  [Content Brief]

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