Apolizumab (Synonyms: 阿泊珠单抗; Hu1D10)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Apolizumab  (Synonyms: 阿泊珠单抗; Hu1D10)

Apolizumab (Hu1D10) 是一种人源化单克隆抗体，抗人类白细胞抗原-DR β 链。Apolizumab 可以在体外介导慢性淋巴细胞白血病 (CLL) 细胞的凋亡。

  • Apolizumab (Synonyms: 阿泊珠单抗; Hu1D10)
  • Apolizumab (Synonyms: 阿泊珠单抗; Hu1D10)

  1. Apolizumab (Synonyms: 阿泊珠单抗; Hu1D10)
  2. Apolizumab (Synonyms: 阿泊珠单抗; Hu1D10)

CAS No. : 267227-08-7

规格 是否有货
1 mg 询价
5 mg 询价

* Please select Quantity before adding items.

Apolizumab 相关产品

•同靶点产品:

•同靶点蛋白产品:

生物活性

Apolizumab (Hu1D10) is a humanized monoclonal anti-Human leukocyte antigen-DR beta-chain antibody. Apolizumab can mediate apoptosis of chronic lymphocytic leukemia (CLL) cells in vitro[1][2].

同型

Human IgG1 kappa
推荐同型对照抗体

Human IgG1 kappa, Isotype Control
种属

Humanized
体外研究
(In Vitro)

Apolizumab 可根据靶抗原的表达诱导 ADCC 和 CMC[2]。
Apolizumab 改变细胞膜极化和通透性，但可能不会直接诱导细胞凋亡[2]。

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Apolizumab 相关抗体:
Clinical Trial

CAS 号

267227-08-7
中文名称

阿泊珠单抗
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Apolizumab (Synonyms: 阿泊珠单抗; Hu1D10)
    Human IgG1 kappa
纯度 & 产品资料
Data Sheet (517 KB) 抗体抑制剂使用指南 (1152 KB)

参考文献

  • [1]. Thomas S Lin, et al. A phase I/II dose escalation study of apolizumab (Hu1D10) using a stepped-up dosing schedule in patients with chronic lymphocytic leukemia and acute leukemia. Leuk Lymphoma. 2009 Dec;50(12):1958-63.  [Content Brief]

    [2]. Matthew L. Hill DO, et al. In Vitro Activity of the Humanized Anti-HLA-DR Antibodies KRN848 and Apolizumab in Non-Hodgkins Lymphoma Cell Lines. Volume 106, Issue 11, 16 November 2005, Page 4826.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务