Cysteamine-d4 hydrochloride(Synonyms: 2-Aminoethanethiol-d4 hydrochloride; 2-Mercaptoethylamine-d4 hydrochloride)

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Cysteamine-d4 hydrochloride (Synonyms: 2-Aminoethanethiol-d4 hydrochloride; 2-Mercaptoethylamine-d4 hydrochloride)

Cysteamine-d4 (2-Aminoethanethiol-d4 hydrochloride) 是 Cysteamine hydrochloride 的氘代物。Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) 是一种可口服的，用于肾病型胱胺酸症得小分子药物，也可作为抗氧化剂。

Cysteamine-d4 hydrochloride(Synonyms: 2-Aminoethanethiol-d4 hydrochloride; 2-Mercaptoethylamine-d4 hydrochloride)

Cysteamine-d4 hydrochloride Chemical Structure

CAS No. : 1219805-04-5

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生物活性

Cysteamine-d4 (2-Aminoethanethiol-d4 hydrochloride) is the deuterium labeled Cysteamine hydrochloride. Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

117.63

Formula

C2H4D4ClNS
CAS 号

1219805-04-5
中文名称

半胱胺盐酸盐 d4 (盐酸盐)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Besouw, M., et al., Cysteamine: an old drug with new potential. Drug Discov Today, 2013. 18(15-16): p. 785-92.

    [3]. de Matos, D.G., et al., Effect of cysteamine on glutathione level and developmental capacity of bovine oocyte matured in vitro. Mol Reprod Dev, 1995. 42(4): p. 432-6.

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