Rhamnetin-d3(Synonyms: 鼠李素 d3)

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Rhamnetin-d3 (Synonyms: 鼠李素 d3)

Rhamnetin-d3 是 Rhamnetin 的氘代物。Rhamnetin 是芫荽中的一种槲皮素衍生物,可抑制分泌型磷脂酶 A2 (phospholipase A2) 的活性,具有抗氧化、抗炎的活性。

Rhamnetin-d3(Synonyms: 鼠李素 d3)

Rhamnetin-d3 Chemical Structure

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生物活性

Rhamnetin-d3 is the deuterium labeled Rhamnetin. Rhamnetin is a quercetin derivative found in Coriandrum sativum, inhibits secretory phospholipase A2, with antioxidant and anti-inflammatory activity[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

319.28

Formula

C16H9D3O7

中文名称

鼠李素 d3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Novo Belchor M, et al. Evaluation of Rhamnetin as an Inhibitor of the Pharmacological Effect of Secretory Phospholipase A2. Molecules. 2017 Aug 31;22(9).

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