3-(3,4-Dimethoxyphenyl)propanoic acid-d10(Synonyms: 3-(3,4-二甲氧基苯)丙酸 d10)

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3-(3,4-Dimethoxyphenyl)propanoic acid-d10 (Synonyms: 3-(3,4-二甲氧基苯)丙酸 d10)

3-(3,4-Dimethoxyphenyl)propanoic acid-d10 是 3-(3,4-Dimethoxyphenyl)propanoic acid 的氘代物。3-(3,4-Dimethoxyphenyl)propanoic acid 是一种具有口服活性的短链脂肪酸 (SCFAs)。3-(3,4-Dimethoxyphenyl)propanoic acid 在体内刺激 γ 球蛋白基因表达和促红细胞生成，可用于 β 血红蛋白病和其他贫血症。

3-(3,4-Dimethoxyphenyl)propanoic acid-d10(Synonyms: 3-(3,4-二甲氧基苯)丙酸 d10)

3-(3,4-Dimethoxyphenyl)propanoic acid-d10 Chemical Structure

CAS No. : 1398065-72-9

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生物活性

3-(3,4-Dimethoxyphenyl)propanoic acid-d10 is the deuterium labeled 3-(3,4-Dimethoxyphenyl)propanoic acid. 3-(3,4-Dimethoxyphenyl)propanoic acid is an orally active short-chain fatty acids (SCFAs). 3-(3,4-Dimethoxyphenyl)propanoic acid stimulates γ globin gene expression, erythropoiesis in vivo and is used for the β hemoglobinopathies and other anemias[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

220.29

Formula

C11H4D10O4
CAS 号

1398065-72-9
中文名称

3-(3,4-二甲氧基苯)丙酸 d10
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Pace BS, et al. Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo. lood. 2002 Dec 15;100(13):4640-8.

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