(Rac)-Atomoxetine D7 hydrochloride(Synonyms: (Rac)-Tomoxetine D7 hydrochloride; (Rac)-LY 139603 D7)

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(Rac)-Atomoxetine D7 hydrochloride (Synonyms: (Rac)-Tomoxetine D7 hydrochloride; (Rac)-LY 139603 D7)

(Rac)-Atomoxetine D7 hydrochloride ((Rac)-Tomoxetine D7 hydrochloride) 是 (Rac)-Atomoxetine hydrochloride 的氘代物。(Rac)-Atomoxetine hydrochloride 是 Atomoxetine hydrochloride 的外消旋形式，Atomoxetine hydrochloride 是去甲肾上腺素重吸收抑制剂，与人 NET，SERT 和 DAT 的放射性配体结合的 Ki 分别为 5 nM，77 nM 和 1451 nM。

(Rac)-Atomoxetine D7 hydrochloride(Synonyms: (Rac)-Tomoxetine D7 hydrochloride; (Rac)-LY 139603 D7)

(Rac)-Atomoxetine D7 hydrochloride Chemical Structure

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生物活性

(Rac)-Atomoxetine D7 hydrochloride ((Rac)-Tomoxetine D7 hydrochloride) is a deuterium labeled (Rac)-Atomoxetine hydrochloride. (Rac)-Atomoxetine hydrochloride is a racemic form of Atomoxetine hydrochloride. Atomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5 nM, 77 nM and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively)[1].

分子量

298.86

Formula

C17H15D7ClNO
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Bymaster FP, Katner JS, Nelson DL et al. Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder. Neuropsychopharmacology. 2002 Nov;27(5):699-711.

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