L-Carnitine-d9 chloride(Synonyms: (R)-Carnitine-d9 chloride; Levocarnitine-d9 chloride)

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L-Carnitine-d9 chloride (Synonyms: (R)-Carnitine-d9 chloride; Levocarnitine-d9 chloride)

L-Carnitine-d9 chloride是 L-Carnitine chloride 的氘代物。L-Carnitine chloride 是一种高度极性的小两性离子,是线粒体β-氧化途径的重要共因子。L-Carnitine chloride 的作用是将长链脂肪酰基辅酶 A 转运到线粒体中,通过 β-氧化降解。L-Carnitine chloride 是一种抗氧化剂。L-Carnitine chloride 可以改善许多先天性代谢错误的代谢失衡。

L-Carnitine-d9 chloride(Synonyms: (R)-Carnitine-d9 chloride; Levocarnitine-d9 chloride)

L-Carnitine-d9 chloride Chemical Structure

CAS No. : 2687961-04-0

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生物活性

L-Carnitine-d9 chloride is the deuterium labeled L-Carnitine chloride. L-Carnitine chloride, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine chloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine chloride is an antioxidant. L-Carnitine chloride can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

206.72

Formula

C7H7D9ClNO3

CAS 号

2687961-04-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

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