Rehmannioside A (Synonyms: 地黄甙 A)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Rehmannioside A (Synonyms: 地黄甙 A) 纯度: ≥98.0%

Rehmannioside A 是一种可以从地黄根中分离得到的神经保护剂。Rehmannioside A 可以抑制促炎介质从小胶质细胞的释放，并在体外促进 M2 极化，从而通过抑制 NF-κB 和 MAPK 信号通路保护共培养神经元免于凋亡 (apoptosis)。Rehmannioside A 可用于脊髓损伤研究。

Rehmannioside A Chemical Structure

CAS No. : 81720-05-0

规格	价格	是否有货
1 mg	￥594	In-stock
5 mg		询价
10 mg		询价

* Please select Quantity before adding items.

Rehmannioside A 相关产品

•相关化合物库:

Natural Product Library Plus
Bioactive Compound Library Plus
Apoptosis Compound Library
Immunology/Inflammation Compound Library
Kinase Inhibitor Library
MAPK Compound Library
NF-κB Signaling Compound Library
Stem Cell Signaling Compound Library
Natural Product Library
Anti-Aging Compound Library
Antioxidant Compound Library
Differentiation Inducing Compound Library
Reprogramming Compound Library
Oxygen Sensing Compound Library
Pyroptosis Compound Library
Traditional Chinese Medicine Active Compound Library
Neuroprotective Compound Library
Anti-Breast Cancer Compound Library
Anti-Lung Cancer Compound Library
Anti-Pancreatic Cancer Compound Library
Anti-Blood Cancer Compound Library
Anti-Cancer Metabolism Compound Library
Neurodegenerative Disease-related Compound Library
Anti-Obesity Compound Library
Angiogenesis-Related Compound Library
Transcription Factor-Targeted Library
Anti-Liver Cancer Compound Library
Antidepressant Compound Library
Anti-inflammatory Traditional Chinese Medicine Active Compound Library
Plant-Sourced Natural Product Library
Anti-Prostate Cancer Compound Library
Anti-Pulmonary Fibrosis Compound Library
Cancer Stem Cells Compound Library
Pain-Related Compound Library
Membrane Protein-targeted Compound Library
Cell Death Library
Serine/Threonine Kinase Inhibitor Library
Anti-Hematopathy Compound Library
Anti-Ovarian Cancer Compound Library
Multi-Target Compound Library
Radioprotector Library

•同靶点产品:

•同靶点蛋白产品:

生物活性

Rehmannioside A is a neuroprotective agent that can be isolated from Rehmanniae radix. Rehmannioside A can inhibit the release of proinflammatory mediators from microglia and promote M2 polarization in vitro, thereby protecting co-cultured neurons from apoptosis by inhibiting NF-κB and MAPK signaling pathways. Rehmannioside A can be used in spinal cord injury research^[1].

分子量

524.47

Formula

C₂₁H₃₂O₁₅

CAS 号

81720-05-0

性状

固体

颜色

White to off-white

中文名称

地黄甙 A

结构分类

Saccharides
Polysaccharides

初始来源

植物
玄参科
地黄

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度 & 产品资料

纯度: ≥98.0%

选择批次：

Data Sheet (532 KB) SDS (393 KB)

COA (202 KB) HNMR (299 KB) MS (68 KB)

产品使用指南 (1538 KB)

参考文献

[1]. Xiao S, et al. Rea regulates microglial polarization and attenuates neuronal apoptosis via inhibition of the NF-κB and MAPK signalings for spinal cord injury repair. J Cell Mol Med. 2021 Feb;25(3):1371-1382. [Content Brief]

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务