5-Hydroxyferulic acid (Synonyms: 5-羟基阿魏酸)

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5-Hydroxyferulic acid  (Synonyms: 5-羟基阿魏酸) 纯度: 99.80%

5-Hydroxyferulic acid 是一种羟基肉桂酸,是苯丙烷途径的代谢产物。5-Hydroxyferulic acid 是芥子酸生物合成中的前体,也是 COMT 非酯化底物。

5-Hydroxyferulic acid                                          (Synonyms: 5-羟基阿魏酸)

5-Hydroxyferulic acid Chemical Structure

CAS No. : 1782-55-4

规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ¥4620 In-stock
1 mg ¥1909 In-stock
5 mg ¥4200 In-stock
10 mg ¥6800 In-stock
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5-Hydroxyferulic acid 相关产品

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生物活性

5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

The product of the alfalfa Caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase (COMT) catalyzed methylation of 5-Hydroxyferulic acid is sinapic acid. 5-Hydroxyferulic acid O-methyltransferase activities (pkat mg-1 protein) in stem material from COMT downregulates transgenic alfalfa[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

5-Hydroxyferulic acid 相关抗体:

分子量

210.18

Formula

C10H10O5

CAS 号

1782-55-4

性状

固体

颜色

Off-white to light yellow

中文名称

5-羟基阿魏酸

结构分类
  • Phenols
  • Polyphenols
  • Ketones, Aldehydes, Acids
初始来源
  • 植物
  • 其他科
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO 中的溶解度 : 100 mg/mL (475.78 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.7578 mL 23.7891 mL 47.5783 mL
5 mM 0.9516 mL 4.7578 mL 9.5157 mL
10 mM 0.4758 mL 2.3789 mL 4.7578 mL

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* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量

=

浓度

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体积

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分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×

体积 (start)

V1

=

浓度 (final)

C2

×

体积 (final)

V2

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动物溶解方案

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

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动物的平均体重

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每只动物的给药体积

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动物数量

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计算结果
工作液所需浓度 : mg/mL

纯度 & 产品资料

纯度: 99.80%

Data Sheet (598 KB) SDS (393 KB)

COA (169 KB) LCMS (268 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. K Parvathi, et al. Substrate Preferences of O-methyltransferases in Alfalfa Suggest New Pathways for 3-O-methylation of Monolignols. Plant J. 2001 Jan;25(2):193-202.  [Content Brief]

    [2]. S Maury, et al. Tobacco O-methyltransferases Involved in Phenylpropanoid Metabolism. The Different Caffeoyl-Coenzyme A/5-hydroxyferuloyl-coenzyme A 3/5-O-methyltransferase and Caffeic acid/5-hydroxyferulic Acid 3/5-O-methyltransferase Classes Have Distinct Substrate Specificities and Expression Patterns. Plant Physiol. 1999 Sep;121(1):215-24.  [Content Brief]

    [3]. Inoue, et al. Substrate Preferences of Caffeic acid/5-hydroxyferulic Acid 3/5-O-methyltransferases in Developing Stems of Alfalfa (Medicago Sativa L.). Arch Biochem Biophys. 2000 Mar 1;375(1):175-82.  [Content Brief]

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