Orotidine (Synonyms: 乳清酸核苷)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Orotidine (Synonyms: 乳清酸核苷) 纯度: ≥95.0%

Orotidine，是一种核苷酸，是 DNA 和 RNA 的嘧啶核苷酸合成过程中的一个中间产物。Orotidine 主要存在于细菌，真菌和植物中。

Orotidine Chemical Structure

CAS No. : 314-50-1

规格	价格	是否有货
1 mg	￥3950	In-stock
5 mg		询价
10 mg		询价

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Orotidine 相关产品

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生物活性

Orotidine, a nucleotide, is an intermediate in pyrimidine nucleotide biosynthesis in RNA and DNA. Orotidine is mainly found in bacteria, fungi and plants^[1]^[2].

IC₅₀ & Target

Human Endogenous Metabolite

体外研究
(In Vitro)

Extant de novo biosynthetic pathway uses Orotidine 50-monophosphate to synthesize the canonical pyrimidine nucleotides in RNA and DNA. In this context, Orotidine is the only nucleotide that is synthesized through a ‘direct intermolecular nucleosidation’ step, with an attack of the fully-preformed nucleobase (orotic acid) on the activated 5-phosphoribosyl-diphosphate as opposed to the purine nucleotides whose heterocyclic rings are constructed stepwise on the sugar^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Orotidine 相关抗体:

分子量

288.21

Formula

C₁₀H₁₂N₂O₈

CAS 号

314-50-1

性状

固体

颜色

Yellow to orange

中文名称

乳清酸核苷

结构分类

Others

初始来源

微生物

内源性代谢物

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度 & 产品资料

纯度: ≥95.0%

选择批次：

Data Sheet (530 KB) SDS (251 KB)

COA (199 KB)

产品使用指南 (1538 KB)

参考文献

[1]. Kim EK, et al. Synthesis of orotidine by intramolecular nucleosidation. Chem Commun (Camb). 2015 Apr 4;51(26):5618-21. [Content Brief]

[2]. A M MICHELSON, et al. A new ribose nucleoside from Neurospora; “orotidine”. Proc Natl Acad Sci U S A. 1951 Jul;37(7):396-9. [Content Brief]

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