3-O-Methyl-DL-DOPA (Synonyms: 3-Methoxytyrosine)

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3-O-Methyl-DL-DOPA  (Synonyms: 3-Methoxytyrosine) 纯度: 99.06%

3-O-Methyl-DL-DOPA 是存在于脑脊液中的内源代谢物,可用于研究癫痫、嘌呤核苷磷酸化酶缺乏和芳香 L 氨基酸脱羧酶缺乏 。

3-O-Methyl-DL-DOPA                                          (Synonyms: 3-Methoxytyrosine)

3-O-Methyl-DL-DOPA Chemical Structure

CAS No. : 7636-26-2

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3-O-Methyl-DL-DOPA 相关产品

相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Metabolism/Protease Compound Library
  • Natural Product Library
  • Phenols Library
  • Food-Sourced Compound Library
  • Human Metabolite Library

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生物活性

3-O-Methyl-DL-DOPA is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Epilepsy, Purine Nucleoside Phosphorylase Deficiency and Aromatic L Amino Acid Decarboxylase Deficiency[1][2][3][4].

体外研究
(In Vitro)

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

3-O-Methyl-DL-DOPA 相关抗体:

分子量

211.21

Formula

C10H13NO4

CAS 号

7636-26-2

性状

固体

颜色

Off-white to light yellow

中文名称

3-O-DL-甲基多巴

结构分类
  • Phenols
  • Monophenols
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

H2O 中的溶解度 : 5 mg/mL (23.67 mM; 超声助溶 (<60°C))

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.7346 mL 23.6731 mL 47.3462 mL
5 mM 0.9469 mL 4.7346 mL 9.4692 mL
10 mM 0.4735 mL 2.3673 mL 4.7346 mL

查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

* 备注:如您选择水作为储备液,请稀释至工作液后,再用 0.22 μm 的滤膜过滤除菌后使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量

=

浓度

×

体积

×

分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×

体积 (start)

V1

=

浓度 (final)

C2

×

体积 (final)

V2

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动物溶解方案

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量

计算结果
工作液所需浓度 : mg/mL

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纯度 & 产品资料

纯度: 99.06%

Data Sheet (599 KB) SDS (0 KB)

COA (191 KB) HNMR (257 KB) RP-HPLC (182 KB) MS (71 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.  [Content Brief]

    [2]. Darin N, et al. Mutations in PROSC Disrupt Cellular Pyridoxal Phosphate Homeostasis and Cause Vitamin-B6-Dependent Epilepsy. Am J Hum Genet. 2016 Dec 1;99(6):1325-1337.  [Content Brief]

    [3]. Ormazabal A, et al. Pyridoxal 5′-phosphate values in cerebrospinal fluid: reference values and diagnosis of PNPO deficiency in paediatric patients. Mol Genet Metab. 2008 Jun;94(2):173-7.  [Content Brief]

    [4]. Abdenur JE, et al. Aromatic l-aminoacid decarboxylase deficiency: unusual neonatal presentation and additional findings in organic acid analysis. Mol Genet Metab. 2006 Jan;87(1):48-53.  [Content Brief]

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