Duramycin (Synonyms: Moli1901; Lancovutide)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Duramycin (Synonyms: Moli1901; Lancovutide) 纯度: 99.46%

Duramycin (Moli1901) 是一种来源于 Streptomyces cinnamoneuma 的羊毛硫细菌素。Duramycin 也是一种抗菌肽。Duramycin 可用于囊性纤维化（CF）的研究。

Duramycin Chemical Structure

CAS No. : 1391-36-2

规格	价格	是否有货
1 mg	￥2000	In-stock
5 mg	￥5900	In-stock
10 mg	￥9200	In-stock
50 mg		询价
100 mg		询价

* Please select Quantity before adding items.

Duramycin 相关产品

•同靶点产品:

•同靶点蛋白产品:

生物活性

Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF)^[1]^[2].

体内研究
(In Vivo)

Evaluation of [⁶⁸Ga]NODAGA-Duramycin as a positron emission tomography (PET) tracer of cell death for whole-body detection of chemotherapy-induced organ toxicity. Organ uptake is analyzed in untreated and doxorubicin, busulfan, and cisplatin-treated mice 2 h after intravenous injection of [⁶⁸Ga]NODAGA-Duramycin. [⁶⁸Ga]NODAGA-Duramycin PET/CT is successfully applied to non-invasively detect chemotherapy-induced organ toxicity with high sensitivity in mice^[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

分子量

2013.28

Formula

C₈₉H₁₂₅N₂₃O₂₅S₃

CAS 号

1391-36-2

性状

固体

颜色

White to off-white

Sequence

Cys-Lys-Gln-Cys-Cys-Ala-Phe-Gly-Pro-Phe-{Abu}-Phe-Val-Cys-Asp-Gly-Asn-{Abu}-Lys-NH2 (Disulfide bridge: Cys1-Abu18, Cys4-Cys14, Cys5-Abu11)

Sequence Shortening

CKQCCAFGPF-{Abu}-FVCDGN-{Abu}-K-NH2 (Disulfide bridge: Cys1-Abu18, Cys4-Cys14, Cys5-Abu11)

初始来源

微生物

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

H₂O 中的溶解度 : 0.5 mg/mL (0.25 mM; 超声助溶)

摩尔计算器
稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

动物溶解方案计算器

请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

每只动物的给药体积

μL

动物数量

只

由于实验过程有损耗，建议您多配一只动物的量

计算结果

工作液所需浓度 : mg/mL

纯度 & 产品资料

纯度: 99.46%

选择批次：

Data Sheet (582 KB) SDS (251 KB)

COA (163 KB) RP-HPLC (265 KB)

产品使用指南 (1538 KB)

参考文献

[1]. Oliynyk I, et al. Effect of duramycin on chloride transport and intracellular calcium concentration in cystic fibrosis and non-cystic fibrosis epithelia. APMIS. 2010 Dec;118(12):982-90. [Content Brief]

[2]. Huo L, et al. Insights into the Biosynthesis of Duramycin. Appl Environ Microbiol. 2017 Jan 17;83(3). pii: e02698-16. [Content Brief]

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Duramycin 相关产品

•同靶点产品:

•同靶点蛋白产品:

摩尔计算器

稀释计算器