1-Stearoyl-2-arachidonoyl-sn-glycerol

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1-Stearoyl-2-arachidonoyl-sn-glycerol  纯度: ≥99.0%

1-Stearoyl-2-arachidonoyl-sn-glycerol 是一种含有多不饱和脂肪酸的二酰基甘油 (DAG)。1-Stearoyl-2-arachidonoyl-sn-glycerol 可以激活 PKC。1-Stearoyl-2-arachidonoyl-sn-glycerol 也可以增强非选择性阳离子通道 (NSCC) 活性。

1-Stearoyl-2-arachidonoyl-sn-glycerol

1-Stearoyl-2-arachidonoyl-sn-glycerol Chemical Structure

CAS No. : 65914-84-3

规格 价格 是否有货 数量
5 mg (15.50 mM * 500 μL in Methyl acetate) ¥4400 In-stock

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1-Stearoyl-2-arachidonoyl-sn-glycerol 相关产品

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生物活性

1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity[1][2].

IC50 & Target

PKC[2]

体外研究
(In Vitro)

1-Stearoyl-2-arachidonoyl-sn-glycerol (0.3-3 μM) 增强气道平滑肌细胞中的非选择性阳离子通道 (NSCC) 活性[1]
1-Stearoyl-2-arachidonoyl-sn-glycerol (0-5 μM) 对 PKCα、PKCδ、PKCγ、PKCε 和 PKCβI 的激活具有显著的刺激作用[2]

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

1-Stearoyl-2-arachidonoyl-sn-glycerol 相关抗体:

分子量

645.01

Formula

C41H72O5

CAS 号

65914-84-3

性状

液体

颜色

Colorless to light yellow

结构分类
  • Others
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Solution, -20°C, 2 years

纯度 & 产品资料

纯度: ≥99.0%

Data Sheet (529 KB) SDS (251 KB)

COA (164 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. Song T, et, al. Inositol 1,4,5-trisphosphate activates TRPC3 channels to cause extracellular Ca2+ influx in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15;309(12):L1455-66.  [Content Brief]

    [2]. Madani S, et, al. Implication of acyl chain of diacylglycerols in activation of different isoforms of protein kinase C. FASEB J. 2001 Dec;15(14):2595-601.  [Content Brief]

    [3]. Glasmacher S, et, al. Characterization of pepcan-23 as pro-peptide of RVD-hemopressin (pepcan-12) and stability of hemopressins in mice. Adv Biol Regul. 2021 May;80:100808.  [Content Brief]

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