Lycorenine (Synonyms: 石蒜裂碱)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Lycorenine  (Synonyms: 石蒜裂碱)

Lycorenine 是一种具有血管减压作用的生物碱。Lycorenine 还显示出抗癌和抗菌活性。

Lycorenine (Synonyms: 石蒜裂碱)

Lycorenine Chemical Structure

CAS No. : 477-19-0

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生物活性

Lycorenine is an alkaloid that has vasodepressor action. Lycorenine also exhibits anticancer and antibacterial activities[1][2][3].

体外研究
(In Vitro)

Lycorenine inhibits the cell viability, with IC50s of 0.8 and 1.2 μg/mL for LMTK and HEPG2 cells, respectively[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Lycorenine 相关抗体:
体内研究
(In Vivo)

Lycorenine (1-10 mg/kg i.v.) produces dose-related decreases in blood pressure and heart rate in anesthetized rats[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

317.38

Formula

C18H23NO4
CAS 号

477-19-0
中文名称

石蒜裂碱
结构分类
  • Alkaloids
  • Pyrrole Alkaloids
初始来源
  • 植物
  • 其他科
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (532 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Miyasaka K, et, al. Pharmacological studies of lycorenine, an alkaloid of Lycoris radiata Herb.: Vasodepressor mechanism in rats. Jpn J Pharmacol. 1979 Aug;29(4):605-22.  [Content Brief]

    [2]. Weniger B, et, al. Cytotoxic activity of Amaryllidaceae alkaloids. Planta Med. 1995 Feb;61(1):77-9.  [Content Brief]

    [3]. Gu D, et, al. Antibacterial Phytosterols and Alkaloids from Lycoris radiate. Natural Product Sciences. 2014 Jou; 20(2): 107-112.

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