6-Hydroxyrubiadin

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
6-Hydroxyrubiadin 

6-Hydroxyrubiadin 是一种天然的蒽酮，是用于炎症和炎症性疾病研究的候选化合物。

6-Hydroxyrubiadin

6-Hydroxyrubiadin Chemical Structure

CAS No. : 87686-86-0

规格 价格 是否有货 数量
1 mg ￥1500 1 周
5 mg ￥3750 1 周
10 mg   询价  
50 mg   询价  

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6-Hydroxyrubiadin 相关产品

•同靶点产品:

•同靶点蛋白产品:

生物活性

6-Hydroxyrubiadin, a natural anthraquinone, may be a potential therapeutic candidate for the treatment of inflammation and inflammatory diseases[1].

体外研究
(In Vitro)

6-hydroxyrubiadin suppresses lipopolysaccharide (LPS)-induced nuclear factor-kappa B activation as well as the phosphorylation of c-Jun N-terminal kinase in RAW 264.7 macrophages[1].
6-hydroxyrubiadin inhibited the expression of tumor necrosis factor (TNF)-a, interleukin (IL)-1b and IL-6 in phorbol myristate acetate (PMA)-primed U937 and RAW 264.7cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

6-Hydroxyrubiadin 相关抗体:
体内研究
(In Vivo)

6-hydroxyrubiadin can reduce the production of pro-inflammatory cytokines and ameliorate acute lung injury (ALI) in a mouse model[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

270.24

Formula

C15H10O5
CAS 号

87686-86-0
结构分类
  • Phenols
  • Polyphenols
  • Ketones, Aldehydes, Acids
初始来源
  • 植物
  • 茜草科
  • 茜草
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (525 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Yanting Wu, et al. In vitro and in vivo inhibitory effects of 6-hydroxyrubiadin on lipopolysaccharide-induced inflammation. Immunopharmacol Immunotoxicol. 2017 Jun;39(3):107-116.  [Content Brief]

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