Waltonitone (Synonyms: 长梗秦艽酮)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Waltonitone  (Synonyms: 长梗秦艽酮)

Waltonitone 是一种从植物天竺葵中提取的乌斯烷型五环三萜。Waltonitone 在体外和体内均显着抑制肝癌细胞的生长并诱导细胞凋亡。

Waltonitone (Synonyms: 长梗秦艽酮)

Waltonitone Chemical Structure

CAS No. : 1252676-55-3

规格 价格 是否有货 数量
2 mg ￥2409 1 周
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

Waltonitone 相关产品

•同靶点产品:

•同靶点蛋白产品:

生物活性

Waltonitone is a ursane-type pentacyclic triterpene isolated from Gentian waltonii Burkill. Waltonitone significantly inhibits hepatocellular carcinoma cells growth and induces apoptosis in vitro and in vivo[1].

体外研究
(In Vitro)

waltonitone (10 μM, 25 μM; for 48 hours) results in an increment of sub-G1 population in BEL-7402 cells[1].
Waltonitone (25 μM; for 48 hours) induces BEL-7402 cells apoptosis[1].
Waltonitone (25 μM; for 48 hours) can effectively activate caspase-3 in BEL-7402 cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Waltonitone 相关抗体:
体内研究
(In Vivo)

Waltonitone (i.v.; 20 mg/kg or 50 mg/kg; once every two days for 16 days) inhibits BEL-7402 tumor growth in male athymic mice (BALB/c nu/nu) in vivo[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

440.70

Formula

C30H48O2
CAS 号

1252676-55-3
中文名称

长梗秦艽酮
结构分类
  • Terpenoids
  • Triterpenes
初始来源
  • 植物
  • 其他科
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (529 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Zhang Z, et al. Waltonitone induces human hepatocellular carcinoma cells apoptosis in vitro and in vivo.Cancer Lett. 2009 Dec 28;286(2):223-31.  [Content Brief]

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务