Neoxanthin (Synonyms: 新黄质)

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Neoxanthin  (Synonyms: 新黄质) 纯度: ≥99.0%

Neoxanthin 是深绿色多叶蔬菜中的一种主要的叶黄素类胡萝卜素，是一种植物激素脱落酸的前体。Neoxanthin 是一种有效的抗氧化剂和集光颜料，诱导细胞凋亡 (apoptosis) 并具有抗癌作用。

Neoxanthin (Synonyms: 新黄质)

Neoxanthin Chemical Structure

CAS No. : 14660-91-4

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生物活性

Neoxanthin is a major xanthophyll carotenoid and a precursor of the plant hormone abscisic acid in dark green leafy vegetables. Neoxanthin is a potent antioxidant and light-harvesting pigment. Neoxanthin induces apoptosis and has anticancer actions[1][2].

体外研究
(In Vitro)

Neoxanthin (20 μM; 72 h) treatment significantly reduces cell viability to 10.9% for PC-3 cells, 15.0% for DU 145 cells, and nearly zero for LNCaP cells, respectively[1].
Neoxanthin strongly inhibits cell growth by suppressing DNA synthesis in C3H10T1/2 cells[1].
In photosynthetic organisms, Neoxanthin is the essential component of both the photosystem I (PSI) and photosystem II (PSII) reaction centers of oxygenic photosynthetic apparatus[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Neoxanthin 相关抗体:
体内研究
(In Vivo)

The gastrointestinal metabolism of Neoxanthin in mice is investigated. Two hours after the oral administration of Neoxanthin (40 nmol/mouse), Neoxanthin is found in the plasma and livers of mice. The concentrations of Neoxanthin is 13.6-9.0 nM in plasma, and 7.3 3.6 pmol/g in liver, respectively. (R/S)-Neochrome is also found in the small intestinal contents of Neoxanthin-administered mice[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

600.87

Formula

C40H56O4
CAS 号

14660-91-4
性状

固体

颜色

Light yellow to yellow

中文名称

新黄质
结构分类
  • Others
初始来源
  • 植物
  • 其他科
  • 微生物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

纯度 & 产品资料

纯度: ≥99.0%

Data Sheet (531 KB) SDS (251 KB)

COA (263 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. E Kotake-Nara, et al. Carotenoids Affect Proliferation of Human Prostate Cancer Cells. J Nutr. 2001 Dec;131(12):3303-6.  [Content Brief]

    [2]. Ramesh Kumar Saini, et al. An Efficient One-Step Scheme for the Purification of Major Xanthophyll Carotenoids From Lettuce, and Assessment of Their Comparative Anticancer Potential. Food Chem. 2018 Nov 15;266:56-65.  [Content Brief]

    [3]. Akira Asai, et al. An Epoxide-Furanoid Rearrangement of Spinach Neoxanthin Occurs in the Gastrointestinal Tract of Mice and in Vitro: Formation and Cytostatic Activity of Neochrome Stereoisomers. J Nutr. 2004 Sep;134(9):2237-43.  [Content Brief]

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