Lucidin primeveroside (Synonyms: Lucidin 3-O-β-primeveroside)

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Lucidin primeveroside  (Synonyms: Lucidin 3-O-β-primeveroside) 纯度: 99.95%

Lucidin primeveroside (Lucidin 3-O-β-primeveroside) 是一种存在于茜草根中的蒽醌衍生物，已被用作着色剂和食品添加剂。Lucidin primeveroside 可以代谢转化为基因毒性化合物 Lucidin，随后形成 Lucidin 特异性 DNA 加合物。

Lucidin primeveroside (Synonyms: Lucidin 3-O-β-primeveroside)

Lucidin primeveroside Chemical Structure

CAS No. : 29706-59-0

规格 价格 是否有货 数量
1 mg ￥4100 In-stock
10 mg 询价
25 mg 询价

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生物活性

Lucidin primeveroside (Lucidin 3-O-β-primeveroside) is an anthraquinone derivative present in madder root, which has been used as a coloring agent and food additive. Lucidin primeveroside can be metabolically converted to genotoxic compound Lucidin, which subsequently forms lucidin-specific DNA adducts[1][2].

体内研究
(In Vivo)

Lucidin primeveroside (0.3% in the diet; 4 weeks or 13 weeks) induces Lucidin-specific DNA adduct formation and increases mutation frequencies in mice[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

564.49

Formula

C26H28O14
CAS 号

29706-59-0
性状

固体

颜色

Light yellow to yellow

结构分类
  • Quinones
  • Anthraquinones
  • Phenols
  • Monophenols
初始来源
  • 植物
  • 茜草科
  • 茜草
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: 99.95%

Data Sheet (532 KB) SDS (0 KB)

COA (199 KB) HNMR (212 KB) CNMR (168 KB) RP-HPLC (489 KB) MS (316 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Yockey OP, et, al. Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase κ. Chem Res Toxicol. 2017 Nov 20;30(11):2023-2032.  [Content Brief]

    [2]. Ishii Y, et, al. Effects of inhibition of hepatic sulfotransferase activity on renal genotoxicity induced by lucidin-3-O-primeveroside. J Appl Toxicol. 2019 Apr;39(4):650-657.  [Content Brief]

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