D-Sedoheptulose 7-phosphate

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D-Sedoheptulose 7-phosphate 

D-Sedoheptulose 7-phosphate 是 septacidin 和 hygromycin B 等七肽的共同前体。D-Sedoheptulose 7-phosphate 通过类似的生物合成途径转化为可转化为 NDP-heptoses。

D-Sedoheptulose 7-phosphate

D-Sedoheptulose 7-phosphate Chemical Structure

CAS No. : 2646-35-7

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D-Sedoheptulose 7-phosphate 相关产品

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生物活性

D-Sedoheptulose 7-phosphate is a common precursor for the heptoses of septacidin (group III) and hygromycin B (group IV). D-Sedoheptulose 7-phosphate can be converted to NDP-heptoses through similar biosynthetic pathways in those compounds [1].

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Sedoheptulose 7-phosphate can be converted to ADP-l-glycero-β-d-manno-heptose by SepB, SepL, and SepC, it involves in ADP-sugar in microbial natural product biosynthesis[1].
SepB is an S-7-P isomerase, SepL involves in the biosynthesis of heptoses of the core region of E. coli LPS, and they catalyze a four-reaction relay converting S-7-P into ADP-d-glycero-β-d-manno-heptose [1].
Septacidin and its analogs are potential anticancer and pain-relief agents[1].
Hygromycin B is an anthelmintic agent practically used in swine and poultry farming[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

D-Sedoheptulose 7-phosphate 相关抗体:

分子量

290.16

Formula

C7H15O10P

CAS 号

2646-35-7

性状

固体

颜色

White to yellow

结构分类
  • Ketones, Aldehydes, Acids
初始来源
  • 内源性代谢物
  • 人肠道微生物代谢物
  • 微生物
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥98.0%

Data Sheet (525 KB) SDS (251 KB)

COA (262 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. Tang W, et al. d-Sedoheptulose-7-phosphate is a common precursor for the heptoses of septacidin and hygromycin B.Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):2818-2823.  [Content Brief]

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