Hamamelitannin (Synonyms: 金缕梅单宁)

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Hamamelitannin  (Synonyms: 金缕梅单宁)

Hamamelitannin 是从 Hamamelis virginiana 树皮中提取的多酚，是一种群体感应 (QS) 抑制剂。Hamamelitannin 通过影响肽聚糖生物合成和 eDNA 释放增加金黄色葡萄球菌生物膜的抗生素敏感性。

Hamamelitannin (Synonyms: 金缕梅单宁)

Hamamelitannin Chemical Structure

CAS No. : 469-32-9

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Hamamelitannin 相关产品

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生物活性

Hamamelitannin, a polyphenol extracted from the bark of Hamamelis virginiana, is a quorum-sensing (QS) inhibitor. Hamamelitannin increases antibiotic susceptibility of staphylococcus aureus biofilms by affecting peptidoglycan biosynthesis and eDNA release[1][2].

体外研究
(In Vitro)

Hamamelitannin displays specific cytotoxic activity against colon cancer cells[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Hamamelitannin 相关抗体:
分子量

484.36

Formula

C20H20O14
CAS 号

469-32-9
中文名称

金缕梅单宁
结构分类
  • Phenols
  • Polyphenols
初始来源
  • 植物
  • 金缕梅科
  • 金缕梅
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (528 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Kiran MD, et al. Discovery of a quorum-sensing inhibitor of drug-resistant staphylococcal infections by structure-based virtual screening. Mol Pharmacol. 2008 May;73(5):1578-86.  [Content Brief]

    [2]. Cobrado L, et al. In vivo antibiofilm effect of cerium, chitosan and hamamelitannin against usual agents of catheter-related bloodstream infections. J Antimicrob Chemother. 2013 Jan;68(1):126-30.  [Content Brief]

    [3]. Sánchez-Tena S, et al. Hamamelitannin displays specific cytotoxic activity against colon cancer cells. J Nat Prod. 2012 Jan 27;75(1):26-33.  [Content Brief]

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