Bruceine E (Synonyms: 鸦胆子素E)

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Bruceine E  (Synonyms: 鸦胆子素E) 纯度: 97.13%

Bruceine E 是鸦胆子种子中的类青霉素,具有降血糖作用。Bruceine E 对非糖尿病小鼠和链脲霉素 (STZ) 诱导的糖尿病大鼠均有降血糖作用。

Bruceine E                                          (Synonyms: 鸦胆子素E)

Bruceine E Chemical Structure

CAS No. : 21586-90-3

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Bruceine E 相关产品

相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Natural Product Library
  • Anti-diabetic Compound Library
  • Terpenoids Library
  • Traditional Chinese Medicine Active Compound Library
  • Plant-Sourced Natural Product Library
  • Heterocyclic Compound Library

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生物活性

Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect[1]. Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ)-induced diabetic rats at lower dose[2].

体内研究
(In Vivo)

Bruceine D and E, isolated from B. javanica seeds, exhibits blood glucose lowering effect in both nondiabetic mice and STZ-induced diabetic rats at lower dose (1 mg/kg b.w.) during 0-8 h screening[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

412.43

Formula

C20H28O9

CAS 号

21586-90-3

性状

固体

颜色

White to off-white

中文名称

鸦胆子素E

结构分类
  • Terpenoids
  • Diterpenoids
初始来源
  • 植物
  • 苦木科
  • 鸦胆子
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: 97.13%

Data Sheet (533 KB) SDS (251 KB)

COA (202 KB) RP-HPLC (143 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. Man F, et al. HPLC-MS/MS method for bioavailability study of bruceines D & E in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 15;1063:183-188.  [Content Brief]

    [2]. Ablat A, et al. Antidiabetic effects of Brucea javanica seeds in type 2 diabetic rats. BMC Complement Altern Med. 2017;17(1):94. Published 2017 Feb 6.  [Content Brief]

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