上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
Furanodiene (Synonyms: 莪术呋喃二烯) 纯度: 99.65%
Furanodiene 是从姜黄中提取的天然萜类化合物。Furanodiene 通过抗血管生成和诱导 ROS 产生,DNA 链断裂和细胞凋亡发挥抗癌作用。Furanodiene 抑制外排转运蛋白 Pgp (P-glycoprotein) 功能并降低 Pgp 蛋白水平。
![Furanodiene Chemical Structure Furanodiene (Synonyms: 莪术呋喃二烯)](http://www.megazyme.com.cn/wp-content/uploads/2024/05/hy-126940.gif)
Furanodiene Chemical Structure
CAS No. : 19912-61-9
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
5 mg | ¥1190 | In-stock | |
10 mg | 询价 | ||
25 mg | 询价 |
* Please select Quantity before adding items.
Furanodiene 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Apoptosis Compound Library
- Immunology/Inflammation Compound Library
- Membrane Transporter/Ion Channel Compound Library
- Metabolism/Protease Compound Library
- NF-κB Signaling Compound Library
- Stem Cell Signaling Compound Library
- Natural Product Library
- Anti-Cancer Compound Library
- Anti-Aging Compound Library
- Antioxidant Compound Library
- Macrocyclic Compound Library
- Oxygen Sensing Compound Library
- Ferroptosis Compound Library
- Medicine Food Homology Compound Library
- Terpenoids Library
- Pyroptosis Compound Library
- Traditional Chinese Medicine Active Compound Library
- Anti-Breast Cancer Compound Library
- Anti-Pancreatic Cancer Compound Library
- Anti-Obesity Compound Library
- Mitochondria-Targeted Compound Library
- Anti-Cancer Natural Product Library
- Anti-inflammatory Traditional Chinese Medicine Active Compound Library
- Plant-Sourced Natural Product Library
- Cancer Stem Cells Compound Library
- Heterocyclic Compound Library
- Marine-Sourced Natural Product Library
- Metabolic Enzyme Compound Library
- Membrane Protein-targeted Compound Library
- Cell Death Library
- Anti-Ovarian Cancer Compound Library
- Radioprotector Library
生物活性 |
Furanodiene is a natural terpenoid isolated from Rhizoma Curcumae. Furanodiene plays anti-cancer effects through anti-angiogenesis and inducing ROS production, DNA strand breaks and apoptosis. Furanodiene suppresseed efflux transporter Pgp (P-glycoprotein) function and reduced Pgp protein level[1]. |
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
体外研究 (In Vitro) |
Furanodiene (1.4, 4.1, 12.2 uM; 48 hours) is effective in treating human JF 305 pancreatic cancer cells and MCF-7 breast cancer cells xenotranplanted into the zebrafish[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||
分子量 |
216.32 |
||||||||||||
Formula |
C15H20O |
||||||||||||
CAS 号 |
19912-61-9 |
||||||||||||
性状 |
固体 |
||||||||||||
颜色 |
Off-white to light yellow |
||||||||||||
中文名称 |
莪术呋喃二烯 |
||||||||||||
结构分类 |
|
||||||||||||
初始来源 |
|
||||||||||||
运输条件 |
Room temperature in continental US; may vary elsewhere. |
||||||||||||
储存方式 |
-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
||||||||||||
溶解性数据 |
In Vitro:
DMSO 中的溶解度 : 100 mg/mL (462.28 mM; 超声助溶 (<60°C); 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO) 配制储备液
查看完整储备液配制表
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2
In Vivo:
请根据您的 实验动物和给药方式 选择适当的溶解方案。 以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:
动物溶解方案计算器
请输入动物实验的基本信息:
给药剂量 mg/kg 动物的平均体重 g 每只动物的给药体积 μL 动物数量 只 由于实验过程有损耗,建议您多配一只动物的量
请输入您的动物体内配方组成:
%
DMSO + %
%
Tween-80 + %
Saline 如果您的动物是免疫缺陷鼠或者体弱鼠,建议 DMSO 中的在最后工作液体系中的占比尽量不超过 2%。 方案所需 助溶剂 包括:DMSO, ,均可在 Shanghai Jinpan Biotech Co Ltd 网站选购。 ,Tween 80,均可在 Shanghai Jinpan Biotech Co Ltd 网站选购。
计算结果
工作液所需浓度 : mg/mL
储备液配制方法 : mg 药物溶于 μL DMSO(母液浓度为 mg/mL)。
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) 免费服务热线:021-50837765
E-mail:sales@jinpanbio.com 技术支持电话:021-50837765 技术支持邮箱:sales@jinpanbio.com 动物实验体内工作液的配制方法 : 取 μL DMSO 储备液,加入 μL 。 μL ,混合均匀至澄清,再加 μL Tween 80,混合均匀至澄清,再加 μL 生理盐水。
连续给药周期超过半月以上,请谨慎选择该方案。
请确保第一步储备液溶解至澄清状态,从左到右依次添加助溶剂。您可采用超声加热 (超声清洗仪,建议频次 20-40 kHz),涡旋吹打等方式辅助溶解。
|
||||||||||||
纯度 & 产品资料 |
纯度: 99.65%
Data Sheet (627 KB) SDS (251 KB)
COA (202 KB) HNMR (248 KB) RP-HPLC (226 KB) MS (67 KB) 产品使用指南 (1538 KB) |
||||||||||||
参考文献 |
|
所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务