Ramiprilat (Synonyms: 雷米普利拉; HOE 498 diacid; Ramipril diacid)

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Ramiprilat  (Synonyms: 雷米普利拉; HOE 498 diacid; Ramipril diacid) 纯度: 97.45%

Ramiprilat (HOE 498 diacid) 是 Ramipril 的活性代谢物，是一种有效的、具有口服活性的血管紧张素转换酶 (ACE) 抑制剂，Ki 值为 7 pM。Ramiprilat 可用于高血压和心力衰竭的研究。

Ramiprilat (Synonyms: 雷米普利拉; HOE 498 diacid; Ramipril diacid)

Ramiprilat Chemical Structure

CAS No. : 87269-97-4

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生物活性

Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research[1].

IC50 & Target

Ki: 7 pM (ACE)[1]
分子量

388.46

Formula

C21H28N2O5
CAS 号

87269-97-4
性状

固体

颜色

White to off-white

中文名称

雷米普利拉
结构分类
  • Alkaloids
  • Pyrrole Alkaloids
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: 97.45%

Data Sheet (527 KB) SDS (393 KB)

COA (197 KB) HNMR (615 KB) RP-HPLC (140 KB) MS (81 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat can be used for high blood pressure and heart failure research[1].  [Content Brief]

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