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5-epi-Arvestonate A
5-epi-Arvestonate A 是一种从绢毛菊 (Seriphidium transiliense) 中分离得到的倍半萜类化合物。5-epi-Arvestonate A 通过激活小眼相关转录因子 (MITF) 和酪氨酸酶家族基因的转录,促进黑色素生成。5-epi-Arvestonate A 通过 JAK/STAT 信号通路抑制永生化人角化细胞 (HaCaT) 中 IFN-γ 趋化因子的表达。
5-epi-Arvestonate A Chemical Structure
CAS No. : 2767066-84-0
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50 mg | 询价 | ||
100 mg | 询价 | ||
250 mg | 询价 |
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生物活性 |
5-epi-Arvestonate A is a sesquiterpenoid isolated from the whole plants of Seriphidium transiliense. 5-epi-Arvestonate A promotes melanogenic production by activating the transcription of microphthalmia-associated transcription factor (MITF) and tyrosinase family genes. 5-epi-Arvestonate A inhibits the expression of IFN-γ-chemokine through the JAK/STAT signaling pathway in immortalized human keratinocyte (HaCaT) cells[1]. |
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体外研究 (In Vitro) |
5-epi-Arvestonate A (50 μM; 48 h) activates the transcription of microphthalmia-associated transcription factor (MITF) and tyrosinase family genes in murine melanoma (B16) cells[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot Analysis[1]
Cell Viability Assay[1]
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分子量 |
298.37 |
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Formula |
C16H26O5 |
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CAS 号 |
2767066-84-0 |
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结构分类 |
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初始来源 |
Seriphidium transiliense |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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纯度 & 产品资料 |
Data Sheet (538 KB) 产品使用指南 (1538 KB)
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参考文献 |
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