Mead ethanolamide

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Mead ethanolamide 

Mead ethanolamide 是一种内源性大麻素受体（cannabinoid receptor）激动剂，对 CB1 和 CB2 的 Kd 值分别为 753 nM 和 1810 nM。

Mead ethanolamide

Mead ethanolamide Chemical Structure

CAS No. : 169232-04-6

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生物活性

Mead ethanolamide is an endogenous cannabinoid receptor agonist with Kd values of 753 nM and 1810 nM against CB1 and CB2, respectively[1].

IC50 & Target

CB1

753 nM (Kd)

CB2

1810 nM (Kd)

体外研究
(In Vitro)

Mead ethanolamide inhibits cAMP accumulation in CHO-hCB1 and CHO-hCB2 cells with IC50s of 431 nM and 156 nM, respectively[1].
Mead ethanolamide (1-1000 nM) inhibits N-type calcium currents in a concentration-dependent manner. Inhibition was halfmaximal at a Mead ethanolamide concentration of 124 ± 19 nM[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Mead ethanolamide 相关抗体:
分子量

349.55

Formula

C22H39NO2
CAS 号

169232-04-6
结构分类
  • Alkaloids
  • Other Alkaloids
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (524 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Priller J, et al. Mead ethanolamide, a novel eicosanoid, is an agonist for the central (CB1) and peripheral (CB2) cannabinoid receptors. Mol Pharmacol. 1995 Aug;48(2):288-92.  [Content Brief]

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