(R)-10,11-Dehydrocurvularin

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(R)-10,11-Dehydrocurvularin 

(R)-10,11-Dehydrocurvularin 是从弯孢菌中分离出来的一种次生代谢产物。(R)-10,11-Dehydrocurvularin 对一些癌细胞具有浓度依赖性细胞毒性，平均 IC50 值为 1.25 µM。

(R)-10,11-Dehydrocurvularin

(R)-10,11-Dehydrocurvularin Chemical Structure

CAS No. : 1095588-70-7

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(R)-10,11-Dehydrocurvularin 相关产品

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生物活性

(R)-10,11-Dehydrocurvularin is a secondary metabolite isolated from Curvularia sp.. (R)-10,11-Dehydrocurvularin displays concentration-dependent cytotoxicity towards human tumor cell lines with a mean IC50 value of 1.25 µM[1].

IC50 & Target

Heat shock response[1]
TGF-β signalling pathway[2]
分子量

290.31

Formula

C16H18O5
CAS 号

1095588-70-7
结构分类
  • Antibiotics
  • Disease Research
  • Antibacterial
  • Antibiotics
  • Disease Research
  • Anticancer
  • Phenols
  • Polyphenols
  • Antibiotics
  • Macrolide Antibiotics
初始来源
  • 微生物

fungus Curvularia sp.
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (529 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Greve H, et al. Apralactone A and a New Stereochemical Class of Curvularins from the Marine-Derived Fungus Curvularia sp. European J Org Chem. 2008;2008(30):10.1002/ejoc.200800522.  [Content Brief]

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