Epoxylathyrol (Synonyms: 环氧续随子醇)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Epoxylathyrol (Synonyms: 环氧续随子醇)

Epoxylathyrol 是从大戟 (Euphorbia boetica) 分离出来的环氧乙氧基醚衍生物。Epoxylathyrol 是一种 P-糖蛋白 (P-gp) 抑制剂，也是 P-gp 介导的多药耐药性 (MDR) 逆转剂。

Epoxylathyrol Chemical Structure

CAS No. : 28649-60-7

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Epoxylathyrol 相关产品

生物活性	Epoxylathyrol, an epoxylathyrane derivative isolated from the Euphorbia boetica, is a P-glycoprotein (P-gp) inhibitor. Epoxylathyrol is a P-gp-mediated multidrug resistance (MDR) reverser^[1]^[2].
体外研究 (In Vitro)	Epoxylathyrol has no significant antiproliferative activity in EPG85-257P (parental; IC₅₀>100 uM), EPG85-257RNOV (multidrug resistance [MDR] phenotype; IC₅₀>100 uM), and EPG85-257RDB (multidrug resistance [MDR] phenotype; IC₅₀=70.53 uM)^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. Epoxylathyrol 相关抗体:
分子量	350.45
Formula	C₂₀H₃₀O₅
CAS 号	28649-60-7
中文名称	环氧续随子醇
结构分类	Terpenoids Diterpenoids
初始来源	植物大戟科大戟
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料	Data Sheet (533 KB) 产品使用指南 (1538 KB)
参考文献	[1]. Mariana Alves Reis, et al. Epoxylathyrane Derivatives as MDR-Selective Compounds for Disabling Multidrug Resistance in Cancer. Front Pharmacol. 2020 May 8;11:599. [Content Brief] [2]. Wei Jiao, et al. Lathyrane diterpenes from Euphorbia lathyris as modulators of multidrug resistance and their crystal structures. Bioorg Med Chem. 2009 Jul 1;17(13):4786-92. [Content Brief]

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