2-Keto-D-Glucose (Synonyms: D-Glucosone; D-Arabino-hexos-2-ulose)

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2-Keto-D-Glucose  (Synonyms: D-Glucosone; D-Arabino-hexos-2-ulose) 纯度: 97.4%

2-Keto-D-Glucose (D-Glucosone) 是导致抗生素皮质酮的次级代谢途径中的关键中间体。2-Keto-D-Glucose 也是 D-葡萄糖转化为 D-果糖的中间产物。2-Keto-D-Glucose存在于各种天然来源中,包括真菌、藻类和贝类。

2-Keto-D-Glucose                                          (Synonyms: D-Glucosone;  D-Arabino-hexos-2-ulose)

2-Keto-D-Glucose Chemical Structure

CAS No. : 1854-25-7

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2-Keto-D-Glucose 相关产品

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生物活性

2-Keto-D-Glucose (D-Glucosone) is a key intermediate in a secondary metabolic pathway leading to the antibiotic Cortalcerone. 2-Keto-D-Glucose is also an intermediate in the conversion of D-glucose into D-fructose. 2-Keto-D-Glucose is found in various natural sources, including fungi, algae, and shellfish[1][2].

体外研究
(In Vitro)

Pyrroloquinoline quinone-dependent 2-keto-D-glucose (2KG) dehydrogenase (2KGDH) has high specificity for the oxidation of 2-Keto-D-Glucose to 2-keto-D-gluconic acid (2KGA). P. aureofaciens (Pa2KGDH) specifically preferred 2KG as a substrate and oxidized the C-1 position of 2KG, indicating that the enzyme is a 2KGDH[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

2-Keto-D-Glucose 相关抗体:

分子量

178.14

Formula

C6H10O6

CAS 号

1854-25-7

性状

固体

颜色

Off-white to light yellow

结构分类
  • Saccharides
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

溶解性数据
In Vitro: 

H2O 中的溶解度 : 0.2 mg/mL (1.12 mM; 超声加热助溶)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 5.6136 mL 28.0678 mL 56.1356 mL
5 mM
10 mM

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* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

* 备注:如您选择水作为储备液,请稀释至工作液后,再用 0.22 μm 的滤膜过滤除菌后使用。

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

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体积 (start)

V1

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浓度 (final)

C2

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体积 (final)

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工作液所需浓度 : mg/mL

纯度 & 产品资料

纯度: 97.4%

Data Sheet (599 KB) SDS (393 KB)

COA (191 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. Sun, Lianhong, et al. Engineering galactose oxidase to increase expression level in E. coli, enhance thermostability, and introduce novel activities. Dissertation (Ph.D.), California Institute of Technology.

    [2]. zawa K, et al. A novel pyrroloquinoline quinone-dependent 2-keto-D-glucose dehydrogenase from Pseudomonas aureofaciens. J Bacteriol. 2015 Apr;197(8):1322-9.  [Content Brief]

    [3]. Te-ning E.Liu, et al. Convenient, laboratory procedure for producing solid d-arabino-hexos-2-ulose (d-glucosone). Carbohydrate Research. Volume 113, Issue 1, 16 February 1983, Pages 151-157.

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