Phosphatidylinositol 4,5-bisphosphate (Synonyms: L-alpha-Phosphatidylinositol-4,5-bisphosphate)

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Phosphatidylinositol 4,5-bisphosphate  (Synonyms: L-alpha-Phosphatidylinositol-4,5-bisphosphate)

Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate) 是细胞膜上的一种磷脂成分。Phosphatidylinositol 4,5-bisphosphate 作为一种主要信使，是磷脂酶 C (PLC) 和磷酸肌醇 3-激酶 (PI3K) 的底物。

Phosphatidylinositol 4,5-bisphosphate (Synonyms: L-alpha-Phosphatidylinositol-4,5-bisphosphate)

Phosphatidylinositol 4,5-bisphosphate Chemical Structure

CAS No. : 245126-95-8

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生物活性

Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate), a phospholipid component of cell membranes, is a substrate for phospholipase C (PLC) and phosphoinositide 3-kinase (PI3K) and as a primary messenger[1][2][3].

分子量

1047.09

Formula

C47H85O19P3
CAS 号

245126-95-8
结构分类
  • Others
初始来源
  • 内源性代谢物
  • 人肠道微生物代谢物
  • 微生物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (521 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Katan M, et, al. Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane. Essays Biochem. 2020 Sep 23;64(3):513-531.  [Content Brief]

    [2]. Arreola J, et, al. Wasted TMEM16A channels are rescued by phosphatidylinositol 4,5-bisphosphate Cell Calcium. 2019 Dec;84:102103.  [Content Brief]

    [3]. Kato M, et, al. Arabidopsis PCaP2 modulates the phosphatidylinositol 4,5-bisphosphate signal on the plasma membrane and attenuates root hair elongation. Plant J. 2019 Aug;99(4):610-625.  [Content Brief]

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