S-(+)-Arundic Acid-d3(Synonyms: (S)ONO-2506-d3; (S)-2-Propyloctanoic acid-d3)

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S-(+)-Arundic Acid-d3 (Synonyms: (S)ONO-2506-d3; (S)-2-Propyloctanoic acid-d3)

S-(+)-Arundic Acid-d3 ((S)ONO-2506-d3) 是 S-(+)-Arundic Acid 的氘代物。S-(+)-Arundic Acid ((S)ONO-2506) 是 Arundic Acid 的 S-对映体。Arundic acid 一种星形胶质细胞调节剂,有用于中风和阿尔茨海默病的研究的潜力。

S-(+)-Arundic Acid-d3(Synonyms: (S)ONO-2506-d3;  (S)-2-Propyloctanoic acid-d3)

S-(+)-Arundic Acid-d3 Chemical Structure

CAS No. : 1246819-98-6

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生物活性

S-(+)-Arundic Acid-d3 ((S)ONO-2506-d3) is the deuterium labeled S-(+)-Arundic Acid. S-(+)-Arundic Acid ((S)ONO-2506) is the S-enantiomer of Arundic Acid. Arundic acid is an astrocyte-modulating agent, has the potential for stroke and Alzheimer’s disease research[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

189.31

Formula

C11H19D3O2

CAS 号

1246819-98-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Kato H, et al. Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTP neurotoxicity in mice. Brain Res. 2004;1030(1):66-73.

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