Enrofloxacin-d5 hydriodide(Synonyms: BAY Vp 2674-d5 hydriodide; PD160788-d5 hydriodide)

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Enrofloxacin-d5 hydriodide (Synonyms: BAY Vp 2674-d5 hydriodide; PD160788-d5 hydriodide)

Enrofloxacin-D5 (BAY Vp 2674-D5) hydriodide 是 Enrofloxacin (monohydrochloride) 的氘代物。Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) 是一种有效的抗生素，作用于 Mycoplasma bovis，MIC90 为 0.312 μg/ mL。

Enrofloxacin-d5 hydriodide(Synonyms: BAY Vp 2674-d5 hydriodide; PD160788-d5 hydriodide)

Enrofloxacin-d5 hydriodide Chemical Structure

CAS No. : 1219795-24-0

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生物活性

Enrofloxacin-D5 (BAY Vp 2674-D5) hydriodide is the deuterium labeled Enrofloxacin (monohydrochloride). Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

492.34

Formula

C19H18D5FIN3O3
CAS 号

1219795-24-0
中文名称

恩诺沙星单盐酸盐 D5 (氢碘化物)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Sulyok KM, et al.Antibiotic susceptibility profiles of Mycoplasma bovis strains isolated from cattle in Hungary, Central Europe. BMC Vet Res. 2014 Oct 25;10:256.

    [3]. Hetze S, et al. Superiority of preventive antibiotic treatment compared with standard treatment of poststroke pneumonia in experimental stroke: a bed to bench approach. J Cereb Blood Flow Metab. 2013 Jun;33(6):846-54.

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