Robenidine-d8 hydrochloride(Synonyms: 盐酸氯苯胍 d8 (盐酸盐))

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Robenidine-d8 hydrochloride (Synonyms: 盐酸氯苯胍 d8 (盐酸盐))

Robenidine-d8 hydrochloride 是 Robenidine hydrochloride 的氘代物。Robenidine hydrochloride 是一种抗球虫药, 对 MRSA 和 VRE 也有抑制活性，其 MIC₅₀ 值分别为 8.1 和 4.7 μM。

Robenidine-d8 hydrochloride Chemical Structure

CAS No. : 1173097-77-2

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生物活性	Robenidine-d8 hydrochloride is the deuterium labeled Robenidine hydrochloride. Robenidine hydrochloride is an anticoccidial agent which is also active against MRSA and VRE with MIC₅₀s of 8.1 and 4.7 μM, respectively.
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	378.71
Formula	C₁₅H₆D₈Cl₃N₅
CAS 号	1173097-77-2
中文名称	盐酸氯苯胍 d8 (盐酸盐)
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Abraham RJ, et al. Robenidine Analogues as Gram-Positive Antibacterial Agents. J Med Chem. 2016 Mar 10;59(5):2126-38. [3]. Liu C, et al. Influence of three coccidiostats on the pharmacokinetics of florfenicol in rabbits. Exp Anim. 2015;64(1):73-9.

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