Clomipramine-d3 hydrochloride(Synonyms: Chlorimipramine-d3 hydrochloride; G-34586-d3 hydrochloride; NSC-169865-d3 hydrochloride)

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Clomipramine-d3 hydrochloride (Synonyms: Chlorimipramine-d3 hydrochloride; G-34586-d3 hydrochloride; NSC-169865-d3 hydrochloride)

Clomipramine-d3 (Chlorimipramine-d3) hydrochloride 是一种氘标记的 Clomipramine hydrochloride。Clomipramine hydrochloride 是 5-羟色胺转运体 (SERT)、去甲肾上腺素转运体 (NET) 和多巴胺转运体 (DAT) 阻断剂，Ki 分别为 0.14，54 和 3 nM。

Clomipramine-d3 hydrochloride(Synonyms: Chlorimipramine-d3 hydrochloride; G-34586-d3 hydrochloride; NSC-169865-d3 hydrochloride)

Clomipramine-d3 hydrochloride Chemical Structure

CAS No. : 1398065-86-5

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生物活性

Clomipramine-d3 (Chlorimipramine-d3) hydrochloride is a deuterium labeled Clomipramine hydrochloride. Clomipramine hydrochloride is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].

分子量

354.33

Formula

C19H21D3Cl2N2
CAS 号

1398065-86-5
中文名称

盐酸氯米帕明 d3 (盐酸盐)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Owens, M.J., et al., Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther, 1997. 283(3): p. 1305-22.

    [2]. McTavish, D. and P. Benfield, Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. Drugs, 1990. 39(1): p. 136-53.

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