Betaxolol-d5(Synonyms: 倍他洛尔 d5)

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Betaxolol-d5 (Synonyms: 倍他洛尔 d5)

Betaxolol-d5 是 Betaxolol 的氘代物。Betaxolol 是一种 β1 肾上腺素受体 (beta1 adrenergic receptor) 阻断剂，可用于高血压和青光眼的研究。

Betaxolol-d5 Chemical Structure

CAS No. : 1189957-99-0

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生物活性	Betaxolol-d5 is the deuterium labeled Betaxolol. Betaxolol is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma.
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	312.46
Formula	C₁₈H₂₄D₅NO₃
CAS 号	1189957-99-0
中文名称	倍他洛尔 d5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Rudoy, C.A. and E.J. Van Bockstaele, Betaxolol, a selective beta(1)-adrenergic receptor antagonist, diminishes anxiety-like behavior during early withdrawal from chronic cocaine administration in rats. Prog Neuropsychopharmacol Biol Psychiatry, 2007. 31(5): p. 1119-29. [3]. Lesar, T.S., Comparison of ophthalmic beta-blocking agents. Clin Pharm, 1987. 6(6): p. 451-63.

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