L-Histidine-13C6,d5,15N3 hydrochloride hydrate(Synonyms: H-His-OH-13C6,d5,15N3 hydrochloride hydrate)

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L-Histidine-13C6,d5,15N3 hydrochloride hydrate (Synonyms: H-His-OH-13C6,d5,15N3 hydrochloride hydrate)

L-Histidine-13C6,d5,15N3 (H-His-OH-13C6,d5,15N3) hydrochloride hydrate 是带有 13C,15N 标记和氘代标记的 L-Histidine hydrochloride hydrate。L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) 是一种内源性代谢产物。

L-Histidine-13C6,d5,15N3 hydrochloride hydrate(Synonyms: H-His-OH-13C6,d5,15N3 hydrochloride hydrate)

L-Histidine-13C6,d5,15N3 hydrochloride hydrate Chemical Structure

CAS No. : 2483829-32-7

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生物活性

L-Histidine-13C6,d5,15N3 (H-His-OH-13C6,d5,15N3) hydrochloride hydrate is the deuterium, 13C-, and 15-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

223.60

Formula

13C6H7D5Cl15N3O3

CAS 号

2483829-32-7

中文名称

L-组氨酸盐酸盐,一水 13C6,d5,15N3 (水合盐酸盐)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

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