Fenoldopam-d4 mesylate(Synonyms: 非诺多泮甲磺酸盐 d4 (甲磺酸盐))

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Fenoldopam-d4 mesylate (Synonyms: 非诺多泮甲磺酸盐 d4 (甲磺酸盐))

Fenoldopam-d4 mesylate 是 Fenoldopam mesylate 的氘代物。Fenoldopam(SKF 82526)甲磺酸盐是多巴胺受体D1选择性激动剂。

Fenoldopam-d4 mesylate Chemical Structure

CAS No. : 1246815-23-5

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生物活性	Fenoldopam-d4 (SKF-82526-d4) mesylate is the deuterium labeled Fenoldopam mesylate. Fenoldopam (SKF 82526) mesylate is a drug and synthetic benzazepine derivative which acts as a selective D1 receptor partial agonist^[1]^[2].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	405.89
Formula	C₁₇H₁₆D₄ClNO₆S
CAS 号	1246815-23-5
中文名称	非诺多泮甲磺酸盐 d4 (甲磺酸盐)
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Grenader, A. and D.P. Healy, Fenoldopam is a partial agonist at dopamine-1 (DA1) receptors in LLC-PK1 cells. J Pharmacol Exp Ther, 1991. 258(1): p. 193-8. [3]. Nichols, A.J., R.R. Ruffolo, Jr., and D.P. Brooks, The pharmacology of fenoldopam. Am J Hypertens, 1990. 3(6 Pt 2): p. 116S-119S.

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