Butoconazole-d5 nitrate(Synonyms: RS 35887-d5)

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Butoconazole-d5 nitrate (Synonyms: RS 35887-d5)

Butoconazole-d5 nitrate (RS 35887-d5) 是 Butoconazole nitrate 的氘代物。Butoconazole nitrate (RS 35887) 是一种咪唑类抗真菌药物，对念珠菌属有活性，对白色念珠菌引起的阴道感染有效。Butoconazole nitrate 被认为可通过抑制类固醇合成而起其他咪唑衍生物的作用。

Butoconazole-d5 nitrate Chemical Structure

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

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生物活性	Butoconazole-d5 nitrate (RS 35887-d5) is the deuterium labeled Butoconazole nitrate. Butoconazole nitrate (RS 35887), an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole nitrate is presumed to function as other imidazole derivatives via inhibition of steroid synthesis^[1]^[2].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	479.82
Formula	C₁₉H₁₃D₅Cl₃N₃O₃S
中文名称	硝酸布康唑 d5 (硝酸盐)
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Anik ST, et al. Extreme vertexes design in formulation development: solubility of butoconazole nitrate in a multicomponent system. J Pharm Sci. 1981;70(8):897-900. [3]. Pharmacology refers to the chemical makeup and behavior of GYNAZOLE 1 (butoconazole nitrate cream).

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