Brimonidine-d4 D-tartrate(Synonyms: 酒石酸溴莫尼定 d4 (D-酒石酸盐))

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Brimonidine-d4 D-tartrate (Synonyms: 酒石酸溴莫尼定 d4 (D-酒石酸盐))

Brimonidine-d4 (UK 14304-d4) D-tartrate 是 Brimonidine D-tartrate 的氘代物。

Brimonidine-d4 D-tartrate(Synonyms: 酒石酸溴莫尼定 d4 (D-酒石酸盐))

Brimonidine-d4 D-tartrate Chemical Structure

CAS No. : 1316758-27-6

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生物活性

Brimonidine-d4 (UK 14304-d4) D-tartrate is the deuterium labeled Brimonidine D-tartrate[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

446.25

Formula

C15H12D4BrN5O6

CAS 号

1316758-27-6

中文名称

酒石酸溴莫尼定 d4 (D-酒石酸盐)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Cambridge, D., UK-14,304, a potent and selective alpha2-agonist for the characterisation of alpha-adrenoceptor subtypes. Eur J Pharmacol, 1981. 72(4): p. 413-5.

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