Oleoylethanolamide-d4(Synonyms: N-Oleoylethanolamide-d4; Oleamide MEA-d4; Oleic acid monoethanolamide-d4)

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Oleoylethanolamide-d4 (Synonyms: N-Oleoylethanolamide-d4; Oleamide MEA-d4; Oleic acid monoethanolamide-d4)

Oleoylethanolamide-d4 (N-Oleoylethanolamide-d4) 是 Oleoylethanolamide 的氘代物。Oleoylethanolamide 是一种高亲和力的内源性 PPAR-α 激动剂，可用于肥胖和动脉硬化的相关研究。

Oleoylethanolamide-d4(Synonyms: N-Oleoylethanolamide-d4; Oleamide MEA-d4; Oleic acid monoethanolamide-d4)

Oleoylethanolamide-d4 Chemical Structure

CAS No. : 946524-36-3

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生物活性

Oleoylethanolamide-d4 (N-Oleoylethanolamide-d4) is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

329.55

Formula

C20H35D4NO2
CAS 号

946524-36-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Chen L, et al. Oleoylethanolamide, an endogenous PPAR-α ligand, attenuates liver fibrosis targeting hepatic stellate cells. Oncotarget. 2015 Dec 15;6(40):42530-40

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