Actarit-d4(Synonyms: 4-Acetylaminophenylacetic acid-d4; MS-932-d4)

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Actarit-d4 (Synonyms: 4-Acetylaminophenylacetic acid-d4; MS-932-d4)

Actarit-d4 (4-Acetylaminophenylacetic acid-d4) 是 Actarit 的氘代物。Actarit 是具有口服活性的。可用以抗风湿研究的化合物，可用于 II 型胶原诱导性关节炎的研究。

Actarit-d4(Synonyms: 4-Acetylaminophenylacetic acid-d4; MS-932-d4)

Actarit-d4 Chemical Structure

CAS No. : 1189999-98-1

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生物活性

Actarit-d4 (4-Acetylaminophenylacetic acid-d4) is the deuterium labeled Actarit. Actarit, an orally active antirheumatic compound, has the potential to treat type II collagen-induced arthritis[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

197.22

Formula

C10H7D4NO3
CAS 号

1189999-98-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Fujisawa H, et al. Effect of actarit on type II collagen-induced arthritis in mice. Arzneimittel-forschung, 01 Jan 1994, 44(1):64-68.

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