Leukotriene E4-d5(Synonyms: LTE4-d5)

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Leukotriene E4-d5 (Synonyms: LTE4-d5)

Leukotriene E4-d5 (LTE4-d5) 是 Leukotriene E4 的氘代物。Leukotriene E4 (LTE4) 是由二肽酶对 LTD4 的作用产生的。Leukotriene E4 是过敏反应的慢反应物质 (SRS-A) 的成分之一。Leukotriene E4 积累在血浆和尿液中，Leukotriene E4 的尿排泄最常被用作哮喘的指标。

Leukotriene E4-d5 Chemical Structure

CAS No. : 1240398-14-4

规格		是否有货
25 μg		询价

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生物活性	Leukotriene E4-d5 (LTE4-d5) is the deuterium labeled Leukotriene E4. Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4. Leukotriene E4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). Leukotriene E4 accumulates in both plasma and urine and urinary excretion of Leukotriene E4 is most often used as an indicator of asthma.
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	444.64
Formula	C₂₃H₃₂D₅NO₅S
CAS 号	1240398-14-4
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

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