(S)-(+)-O-Desmethyl Venlafaxine D6(Synonyms: 去甲文拉法辛 Desmethyl Venlafaxine D6)

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(S)-(+)-O-Desmethyl Venlafaxine D6 (Synonyms: 去甲文拉法辛 Desmethyl Venlafaxine D6)

(S)-(+)-O-Desmethyl Venlafaxine D6 是 (S)-(+)-O-Desmethyl Venlafaxine 的氘代物。O-Desmethyl Venlafaxine 是 Venlafaxine 的活性代谢产物。Venlafaxine (HY-B0196) 是 5-羟色胺-去甲肾上腺素再摄取抑制剂 (SNRI) 类的抗抑郁剂。

(S)-(+)-O-Desmethyl Venlafaxine D6(Synonyms: 去甲文拉法辛 Desmethyl Venlafaxine D6)

(S)-(+)-O-Desmethyl Venlafaxine D6 Chemical Structure

CAS No. : 1062609-99-7

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生物活性

(S)-(+)-O-Desmethyl Venlafaxine D6 is the deuterium labeled (S)-(+)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].

分子量

269.41

Formula

C16H19D6NO2

CAS 号

1062609-99-7

中文名称

去甲文拉法辛 Desmethyl Venlafaxine D6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28.

    [2]. F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.

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