N-Acetyl sulfadiazine-d4

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
N-Acetyl sulfadiazine-d4 

N-Acetyl sulfadiazine-d4 是 Triton X-45(n=4) 的氘代物。Triton X-45 (n=4) 是一种非离子表面活性剂，具有较低的亲水-亲油平衡 (HLB) 值，可在室温下分散在水溶液中，其 Krafft 点高于室温。Triton X-45 具有研究丙型肝炎病毒 (HCV) 的潜力。

N-Acetyl sulfadiazine-d4

N-Acetyl sulfadiazine-d4 Chemical Structure

CAS No. : 1219149-66-2

规格 是否有货
1 mg Check price and availability
10 mg Check price and availability

* Please select Quantity before adding items.

生物活性

N-Acetyl sulfadiazine-d4 is the deuterium labeled Triton X-45(n=4). Triton X-45 (n=4), a nonionic surfactant with a low hydrophile-lypophile balance (HLB) value and dispersible in aqueous solution at room temperature, has a Krafft point above the room temperature. Triton X-45 has the potential for the research of the hepatitis C virus (HCV)[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

296.34

Formula

C12H8D4N4O3S
CAS 号

1219149-66-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Wang Z, et al. Cloud point of nonionic surfactant Triton X-45 in aqueous solution. Colloids Surf B Biointerfaces. 2008;61(1):118-122.

    [3]. Chou ML, et al. TnBP⁄Triton X-45 treatment of plasma for transfusion efficiently inactivates hepatitis C virus. PLoS One. 2015;10(2):e0117800. Published 2015 Feb 6.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务