Ciprofloxacin-d8 hydrochloride hydrate(Synonyms: Bay-09867-d8 hydrochloride hydrate)

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Ciprofloxacin-d8 hydrochloride hydrate (Synonyms: Bay-09867-d8 hydrochloride hydrate)

Ciprofloxacin-d8 (Bay-09867-d8 ) hydrochloride monohydrate 是 Ciprofloxacin (monohydrochloride) 的氘代物。Ciprofloxacin monohydrochloride (Bay-09867 monohydrochloride) 是一种氟喹诺酮类抗生素，具有高效的抗菌活性。

Ciprofloxacin-d8 hydrochloride hydrate(Synonyms: Bay-09867-d8 hydrochloride hydrate)

Ciprofloxacin-d8 hydrochloride hydrate Chemical Structure

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生物活性

Ciprofloxacin-d8 (Bay-09867-d8) hydrochloride monohydrate is the deuterium labeled Ciprofloxacin hydrochloride monohydrate. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
Formula

C17D8H10FN3O3.HCl.xH2O
中文名称

盐酸环丙沙星 d8 (水合盐酸盐)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Peltzer PM, et al. Ecotoxicity of veterinary enrofloxacin and ciprofloxacin antibiotics on anuran amphibian larvae. Environ Toxicol Pharmacol. 2017 Feb 4. pii: S1382-6689(17)30029-7.

    [3]. Steenbergen J, et al. In Vitro and In Vivo Activity of Omadacycline Against Two Biothreat Pathogens: Bacillus anthracis and Yersinia pestis. Antimicrob Agents Chemother. 2017 Feb 21.

    [4]. Hamblin KA, et al. Inhaled Liposomal Ciprofloxacin Protects against a Lethal Infection in a Murine Model of Pneumonic Plague. Front Microbiol. 2017 Feb 6;8:91.

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