Molindone-d8(Synonyms: (±)-Molindone-d8; SPN-810M-d8)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Molindone-d8 (Synonyms: (±)-Molindone-d8; SPN-810M-d8)

Molindone-d8 ((±)-Molindone-d8) 是 Molindone 的氘代物。Molindone 是一种抗精神病药，有潜力用于精神分裂症的研究，可以通过阻断大脑中多巴胺的作用，从而降低精神病。

Molindone-d8 Chemical Structure

CAS No. : 1189805-13-7

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生物活性	Molindone-d8 ((±)-Molindone-d8) is the deuterium labeled Molindone. Molindone hydrochloride (EN-1733A) is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses^[1]^[2].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	284.42
Formula	C₁₆H₁₆D₈N₂O₂
CAS 号	1189805-13-7
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Yu C, et al. In vitro pharmacological characterization of SPN-810M (molindone). J Exp Pharmacol. 2018;10:65-73. Published 2018 Nov 21. [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

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