Tebuconazole-d9(Synonyms: 戊唑醇 d9)

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Tebuconazole-d9 (Synonyms: 戊唑醇 d9)

Tebuconazole-d9 是 Tebuconazole 的氘代物。Tebuconazole 是一种农用唑类杀菌剂也能抑制 CYP51 ，对于白色念珠菌 CYP51 (CaCYP51) 和截段的人 CYP51 (Δ60HsCYP51) 的 IC₅₀ 值分别为 0.9 和 1.3 μM。

Tebuconazole-d9 Chemical Structure

CAS No. : 1246818-83-6

规格	价格	是否有货
1 mg	￥5900	询问价格 & 货期

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生物活性	Tebuconazole-d9 is the deuterium labeled Tebuconazole. Tebuconazole is an agricultural azole fungicide which can also inhibit CYP51 with IC₅₀s of 0.9 and 1.3 μM for Candida albicans CYP51 (CaCYP51) and truncated Homo sapiens CYP51 (Δ60HsCYP51), respectively.
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	316.87
Formula	C₁₆H₁₃D₉ClN₃O
CAS 号	1246818-83-6
中文名称	戊唑醇 d9
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Warrilow AG, et al. Azole affinity of sterol 14α-demethylase (CYP51) enzymes from Candida albicans and Homo sapiens. Antimicrob Agents Chemother. 2013 Mar;57(3):1352-60.

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