Clobetasone butyrate-d7

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Clobetasone butyrate-d7 

Clobetasone butyrate-d7 是 Clobetasone butyrate 的氘代物。Clobetasone butyrate 是一种糖皮质类固醇 (glucocorticoid)，具有局部抗炎活性，尤其是在皮肤上。Clobetasone butyrate 可用于缓解皮质类固醇反应性症状，包括特应性皮炎和牛皮癣。

Clobetasone butyrate-d7

Clobetasone butyrate-d7 Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Clobetasone butyrate-d7 is the deuterium labeled Clobetasone butyrate. Clobetasone butyrate is a synthetic glucocorticoid and has topical anti-inflammatory activity especially in skin. Clobetasone butyrate can be used to relieve corticosteroid-responsive dermatoses, including atopic dermatitis and psoriasis[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

486.02

Formula

C26H25D7ClFO5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Munro DD, et al. Clobetasone butyrate, a new topical corticosteroid: clinical activity and effects on pituitary-adrenal axis function and model of epidermal atrophy.

    [3]. Michael Stewart, et al. Clobetasone butyrate for inflammatory skin conditions.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务