Desoxycorticosterone pivalate-d9(Synonyms: DOCP-d9)

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Desoxycorticosterone pivalate-d9 (Synonyms: DOCP-d9)

Desoxycorticosterone pivalate-d9 (DOCP-d9) 是 Desoxycorticosterone pivalate 的氘代物。Desoxycorticosterone pivalate (DOCP) 是一种盐皮质激素，是地塞米松的类似物。Desoxycorticosterone pivalate 用于犬肾上腺皮质功能减退症的研究。

Desoxycorticosterone pivalate-d9(Synonyms: DOCP-d9)

Desoxycorticosterone pivalate-d9 Chemical Structure

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生物活性

Desoxycorticosterone pivalate-d9 (DOCP-d9) is the deuterium labeled Desoxycorticosterone pivalate. Desoxycorticosterone pivalate (DOCP) is a mineralocorticoid hormone and an analog of Desoxycorticosterone. Desoxycorticosterone pivalate is used for the management of canine hypoadrenocorticism[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

423.63

Formula

C26H29D9O4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Sieber-Ruckstuhl NS, et al. Evaluation of a low-dose desoxycorticosterone pivalate treatment protocol for long-term management of dogs with primary hypoadrenocorticism. J Vet Intern Med. 2019 May;33(3):1266-1271.

    [3]. Masticatory Muscle Myositis: Pathogenesis, Diagnosis, and Treatment.

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